Financial toxicity of cancer has so far been discussed primarily in the US health care system and is\nassociated with higher morbidity and mortality. In European health care systems, the socio-economic impact of\ncancer is poorly understood. This study investigates the financial burden and patient-reported outcomes of\nneuroendocrine (NET) or colorectal (CRC) cancer patients at a German Comprehensive Cancer Center.\nMethods: This prospective cross-sectional study surveyed 247 advanced stage patients (n = 122 NET/n = 125 CRC)\nat the National Center for Tumor Diseases, in Germany about cancer-related out-of-pocket costs, income loss,\ndistress, and quality of life. Multiple linear regression analysis was performed to demonstrate the effects of\neconomic deterioration on patientsâ?? quality of life and distress............
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